Budesonide Reduces Bile Acid Malabsorption

Budesonide reduces bile acid malabsorption as can be seen in the following study which used the SeHCAT scan. The authors commented ‘The SeHCAT values increased significantly during budesonide treatment and reached a level corresponding to the healthy control group‘.

Bajor A, Kilander A, Galman C, Rudling M, Ung K.A, Budesonide treatment is associated with increased bile acid absorption in collagenous colitis.Aliment Pharmacol Ther. 2006; 24: 1643-1649

We can now construct a hypothesis to explain the underlying mechanisms of collagenous colitis.