{"id":4964,"date":"2020-06-04T12:38:37","date_gmt":"2020-06-04T12:38:37","guid":{"rendered":"http:\/\/ibshypo.com\/?page_id=4964"},"modified":"2020-06-19T10:44:52","modified_gmt":"2020-06-19T10:44:52","slug":"collagenous-colitis-summary","status":"publish","type":"page","link":"https:\/\/ibshypo.com\/index.php\/collagenous-colitis-summary\/","title":{"rendered":"Collagenous Colitis &#8211; Summary"},"content":{"rendered":"\n<p class=\"has-background has-light-green-cyan-background-color\">Collagenous colitis (CC) causes diarrhoea, increased collagen layer thickness and bile acid malabsorption (BAM).  There is evidence of a noxious factor in the faecal stream.  It was proposed that bile acid might be this noxious factor and treatment with budesonide and colesevelam could break the CC \/ BAM vicious circle.<\/p>\n\n\n\n<p class=\"has-background has-very-light-gray-background-color\">It was possible to taper down budesonide therapy whilst using colesevelam to protect the gut from bile acids.  This resulted in a complete cure with no need for further medication.<\/p>\n\n\n\n<p class=\"has-background has-very-light-gray-background-color\">Protecting the gut form BAM whilst tapering down budesonide therapy was a successful strategy.  I suggest patients ask their gastroenterologist if they can trial this therapy.<\/p>\n\n\n\n<p class=\"has-background has-light-green-cyan-background-color\">Some patients with severe CC need an ileostomy because budesonide therapy isn&#8217;t effective.  They may be able to avoid surgery by using combined budesonide \/ colesevelam therapy.<br><\/p>\n\n\n\n<hr class=\"wp-block-separator\"\/>\n","protected":false},"excerpt":{"rendered":"<p>Collagenous colitis (CC) causes diarrhoea, increased collagen layer thickness and bile acid malabsorption (BAM). There is evidence of a noxious factor in the faecal stream. It was proposed that bile acid might be this noxious factor and treatment with budesonide and colesevelam could break the CC \/ BAM vicious circle. It was possible to taper [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/ibshypo.com\/index.php\/wp-json\/wp\/v2\/pages\/4964"}],"collection":[{"href":"https:\/\/ibshypo.com\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ibshypo.com\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ibshypo.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ibshypo.com\/index.php\/wp-json\/wp\/v2\/comments?post=4964"}],"version-history":[{"count":24,"href":"https:\/\/ibshypo.com\/index.php\/wp-json\/wp\/v2\/pages\/4964\/revisions"}],"predecessor-version":[{"id":5020,"href":"https:\/\/ibshypo.com\/index.php\/wp-json\/wp\/v2\/pages\/4964\/revisions\/5020"}],"wp:attachment":[{"href":"https:\/\/ibshypo.com\/index.php\/wp-json\/wp\/v2\/media?parent=4964"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}